DJ-1 polyclonal (N-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP6407a
Catalog Number: AC-AP6407a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB8160
Applications: IF, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB8160
Applications: IF, WB
Datasheet
Request Information
Background:
Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 40 years, slow progression and initial good response to levodopa.
Other Names:
Protein DJ-1, 34--, Oncogene DJ1, Parkinson disease protein 7, PARK7
Target/Specificity:
This DJ-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DJ-1.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: PARK7 (HGNC:16369)
Gene ID: 11315
Primary Accession: Q99497
NCBI Accession: NP_001116849.1;NP_009193.2
Other Accession: Q99LX0; Q5XJ36; Q5E946
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 40 years, slow progression and initial good response to levodopa.
Other Names:
Protein DJ-1, 34--, Oncogene DJ1, Parkinson disease protein 7, PARK7
Target/Specificity:
This DJ-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DJ-1.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: PARK7 (HGNC:16369)
Gene ID: 11315
Primary Accession: Q99497
NCBI Accession: NP_001116849.1;NP_009193.2
Other Accession: Q99LX0; Q5XJ36; Q5E946
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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