DKK2 monoclonal, anti-human, mouse
€0.00
In stock
SKU
AC-AM8643b
Catalog Number: AC-AM8643b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1833CT856.7.20
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1833CT856.7.20
Applications: WB
Datasheet
Request Information
Background:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Other Names:
Dickkopf-related protein 2, Dickkopf-2, Dkk-2, hDkk-2, DKK2
Target/Specificity:
This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.
Antigen Type: Recombinant Protein
Gene Name: DKK2
Gene ID: 27123
Primary Accession: Q9UBU2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Other Names:
Dickkopf-related protein 2, Dickkopf-2, Dkk-2, hDkk-2, DKK2
Target/Specificity:
This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.
Antigen Type: Recombinant Protein
Gene Name: DKK2
Gene ID: 27123
Primary Accession: Q9UBU2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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