DKK2 Polyclonal Antibody

Background:
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).

Research Area: Cancer, Stem Cells

Synonyms:
Dickkopf 2, Dickkopf gene 2 , Dickkopf homolog 2, Dickkopf related protein 2, Dickkopf WNT signaling pathway inhibitor 2, Dickkopf-2, Dickkopf-related protein 2, Dickkopf2, DKK 2, Dkk-2, Dkk2, DKK2, hDkk 2, hDkk-2, hDkk2

Immunogen: Recombinant protein of human DKK2

Swissprot: Q9UBU2
Gene Accession: BC126328

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.8 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-14953/sc-30786/sc-30787/sc-130738/sc-25517