DLC-1 polyclonal antibody, anti-human, mouse, rat

Background:
DLC1 encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

Research Area: Tags & Cell Markers

Synonyms: DLC1, ARHGAP7, KIAA1723, STARD12, Rho GTPase-activating protein 7, Deleted in liver cancer 1 protein, DLC-1, HP protein, Rho-type GTPase-activating protein 7, START domain-containing protein 12, StARD

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year