DLD Polyclonal Antibody

Background:
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Dehydrogenase complex, E3 component, Diaphorase, Dihydrolipoamide dehydrogenase, Dihydrolipoyl dehydrogenase, Dihydrolipoyl dehydrogenase mitochondrial, dld, DLDD, DLDH, DLDH, E3, E3 branched chain aplha-keto acid, E3 component of pyruvate dehydrogenase, E3 component of pyruvate dehydrogenase complex 2 oxo glutarate complex branched chain keto acid dehydrogenase complex, GCSL, Glycine cleavage system L protein, Glycine cleavage system protein L, LAD, lipoamide dehydrogenase, Lipoamide reductase, Lipoyl dehydrogenase, mitochondrial, OTTHUMP00000206744, OTTHUMP00000206746, OTTHUMP00000206748, OTTHUMP00000206749, PHE 3, PHE3, Pyruvate dehydrogenase component E3

Immunogen: Recombinant protein of human DLD

Swissprot: P09622
Gene Accession: BC018696

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-55932