DLG4 polyclonal, anti-human, mouse, rat

Background:
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

Synonyms: PSD95, SAP-90, SAP90, Disks large homolog 4, Postsynaptic density protein 95

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human DLG4

Gene Symbol: DLG4

Gene ID: 1742

Swiss prot: P78352

Calculated MW: 85kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.