DLK polyclonal, anti-human
€0.00
In stock
SKU
AC-AP11212A
Catalog Number: AC-AP11212A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15965
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15965
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
Other Names:
Protein delta homolog 1, DLK-1, pG2, Fetal antigen 1, FA1, DLK1, DLK
Target/Specificity:
This DLK Antibody is generated from rabbits immunized with a recombinant protein of human DLK.
Antigen Type: Recombinant Protein
Gene Name: DLK1
Gene ID: 8788
Primary Accession: P80370
NCBI Accession: NP_003827.3
Other Accession: NP_003827.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
Other Names:
Protein delta homolog 1, DLK-1, pG2, Fetal antigen 1, FA1, DLK1, DLK
Target/Specificity:
This DLK Antibody is generated from rabbits immunized with a recombinant protein of human DLK.
Antigen Type: Recombinant Protein
Gene Name: DLK1
Gene ID: 8788
Primary Accession: P80370
NCBI Accession: NP_003827.3
Other Accession: NP_003827.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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