DLK1 Polyclonal Antibody

Background:
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity.

Research Area: Cancer, Neuroscience, Signal Transduction, Stem Cells

Synonyms:
Adipocyte differentiation inhibitor protein, Brevideltin, Delta like 1 homolog, Delta like homolog, Delta like protein, Delta1, DLK 1, DLK, DLK-1, DLK1, DLK1, FA 1, FA1, Fetal antigen 1, pG2, Preadipocyte factor 1, Pref 1, Pref, Pref1, Protein delta homolog 1, Secredeltin, ZOG

Immunogen: Fusion protein of human DLK1

Swissprot: P80370
Gene Accession: BC007741

Calculated MW: 41 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.