DLK1 Polyclonal Antibody

Background:
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.

Research Area: Cancer, Neuroscience, Signal Transduction, Stem Cells

Synonyms:
DLK1, DLK, DLK-1, Delta1, FA1, PREF1, Pref-1, ZOG, pG2

Immunogen: Recombinant protein of human DLK1

Swissprot: P80370
Gene ID: 8788

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.