DLL4 (clone DL86-3AG), anti-human
€204.00
In stock
SKU
ARP-23-A0080
Catalog Number: 23-A0080
Size: 25 µg
Isotype: Mouse IgG1 kappa
Size: 25 µg
Isotype: Mouse IgG1 kappa
Decription:
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Synonyms: Delta-like Protein 4, Delta4
Clone: DL86-3AG
Isotype: Mouse IgG1 kappa
Immunogen: Recombinant human DLL4 (extracellular domain).
Reactivity: human
Specificity: Recognizes human DLL4.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct and indirect: 1:2'000-1:5'000)
Western Blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Synonyms: Delta-like Protein 4, Delta4
Clone: DL86-3AG
Isotype: Mouse IgG1 kappa
Immunogen: Recombinant human DLL4 (extracellular domain).
Reactivity: human
Specificity: Recognizes human DLL4.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct and indirect: 1:2'000-1:5'000)
Western Blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
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