DLL4 polyclonal, anti-human, rat

Background:
The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.

Alternative Name:
Delta4, DLL4, UNQ1895/PRO4341, AOS6, Delta 4, delta 4 precursor, Delta ligand 4, delta ligand 4 precursor, Delta like 4, Delta like 4 homolog, Delta like 4 protein, Delta like canonical Notch ligand 4, Delta like protein 4, Delta-like 4 (Drosophila), Delta-like protein 4, Delta4, DLL 4, Dll4, DLL4, Drosophila Delta homolog 4, hdelta2, Homeobox protein DLL-4, MGC126344, Notch ligand delta 2, Notch ligand DLL4, Notch ligand DLL4 precursor, XDLL-4,

Application Dilution:
WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: DLL4 polyclonal antibody detects endogenous levels of DLL4 protein.

Immunogen:
Peptide.

MW: 74 kDa

Swiss-Prot: Q9NR61(Human) D3ZHH1(Rat)

Purification & Purity:
Peptide affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.