DLX4 Polyclonal Antibody

Background:
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
Beta protein 1, BP1, Distal less homeo box 7, Distal less homeo box 9, distal-less homeobox 4, DLX4, DLX4, DLX7, DLX8, DLX9, Homeobox protein DLX-4, Homeobox protein DLX-7, Homeobox protein DLX-8, Homeobox protein DLX4

Immunogen: Recombinant protein of human DLX4

Swissprot: Q92988
Gene Accession: BC016145

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-18146/sc-18145