DMAP1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Synonyms: DNMAP1, DNMTAP1, EAF2, MEAF2, SWC4

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human DMAP1

Gene Symbol: DMAP1

Gene ID: 55929

Swiss prot: Q9NPF5

Calculated MW: 53kDa

Recommended dilution:
WB 1:1000-4000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.