DMBT1 polyclonal (C-Term), anti-rat

DMBT1 polyclonal (C-Term), anti-rat

€0.00
In stock
SKU
AC-AP21824b
Catalog Number: AC-AP21824b
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB53896
Applications: WB
Datasheet

Request Information
Background:
May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly- sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.

Other Names:
Deleted in malignant brain tumors 1 protein, Glycoprotein 340, Gp-340, Hensin, Salivary agglutinin, SAG, Surfactant pulmonary-associated D-binding protein, DMBT1, GP340

Target/Specificity:
This DMBT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2160-2192 amino acids from human DMBT1.

Gene Name: DMBT1 {ECO:0000303|PubMed:28397838, ECO:0000312|HGNC:HGNC:2926}
Gene ID: 1755
Primary Accession: Q9UGM3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
More Information
Is Featured? No
Write Your Own Review
You're reviewing:DMBT1 polyclonal (C-Term), anti-rat