DMGDH polyclonal (C-term), anti-human
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In stock
SKU
AC-AP18005B
Catalog Number: AC-AP18005B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23867
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23867
Applications: WB
Datasheet
Request Information
Background:
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum.
Other Names:
Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH, DMGDH
Target/Specificity:
This DMGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 836-864 amino acids from the C-terminal region of human DMGDH.
Antigen Region:
836-864
Antigen Type: Synthetic Peptide
Gene Name: DMGDH
Gene ID: 29958
Primary Accession: Q9UI17
NCBI Accession: NP_037523.2
Other Accession: NP_037523.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum.
Other Names:
Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH, DMGDH
Target/Specificity:
This DMGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 836-864 amino acids from the C-terminal region of human DMGDH.
Antigen Region:
836-864
Antigen Type: Synthetic Peptide
Gene Name: DMGDH
Gene ID: 29958
Primary Accession: Q9UI17
NCBI Accession: NP_037523.2
Other Accession: NP_037523.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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