DMRT1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Description:
Rabbit IgG polyclonal antibody for Doublesex- and mab-3-related transcription factor 1 (DMRT1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
CT154 antibody, DM domain expressed in testis 1 antibody, DM domain expressed in testis protein 1 antibody, DM domain gene expressed in testis antibody, DMRT 1 antibody, dmrt1 antibody, DMRT1_HUMAN antibody, DMT 1 antibody, DMT1 antibody, Doublesex and mab 3 related transcription factor 1 antibody, Doublesex- and mab-3-related transcription factor 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human DMRT1 (98-128aa RDCQCKKCNLIAERQRVMAAQVALRRQQAQE), different from the related mouse sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.