DMRTA1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60655
Background:
DMRTA1 (DMRT-like family A1), also known as DMO, is a 504 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed in prostate, liver, pancreas and kidney and present at lower levels in ovary and testis, DMRTA1 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Alternative Name:
Doublesex- and mab-3-related transcription factor A1, DMRTA1, DMO
Application Dilution: WB: 1:500~1:1000
Specificity: DMRTA1 polyclonal antibody detects endogenous levels of DMRTA1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human DMRTA1
MW: ~ 53 kDa
Swis Prot.: Q5VZB9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
DMRTA1 (DMRT-like family A1), also known as DMO, is a 504 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed in prostate, liver, pancreas and kidney and present at lower levels in ovary and testis, DMRTA1 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Alternative Name:
Doublesex- and mab-3-related transcription factor A1, DMRTA1, DMO
Application Dilution: WB: 1:500~1:1000
Specificity: DMRTA1 polyclonal antibody detects endogenous levels of DMRTA1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human DMRTA1
MW: ~ 53 kDa
Swis Prot.: Q5VZB9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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