DNA-PK polyclonal, anti-human, mouse, rat, hamster antibody
€295.00
In stock
SKU
AC-ABV10103-100
Catalog Number: AC-ABV10103-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
DNA-dependent protein kinase (DNA-PK) is made up of 3 subunits, 2 Ku proteins and a large catalytic subunit (DNA-PKcs). DNA-PKcs falls into the phosphatidyl-inositol 3-kinase superfamily altho µgh it does have serine/threonine protein kinase activity. This subunit migrates on SDS-PAGE gels as an intact and smaller processed form. In vitro, DNA-PK phosphorylates several transcription factors and other DNA-binding proteins and is believed to play a role in DNA damage recognition, repair and transcription. There is evidence to s µggest that DNA-PKcs may be a critical target for proteolysis by a caspase in apoptosis.
Other Names:
PRKDC, XRCC7 , p460, DNPK1, HYRC, HYRC1 , DNAPK , p350
Primary Accession: P78527
Gene Name: PRKDC
Gene ID: 5591
Concentration (mg/ml): 0.5 mg/ml
DNA-dependent protein kinase (DNA-PK) is made up of 3 subunits, 2 Ku proteins and a large catalytic subunit (DNA-PKcs). DNA-PKcs falls into the phosphatidyl-inositol 3-kinase superfamily altho µgh it does have serine/threonine protein kinase activity. This subunit migrates on SDS-PAGE gels as an intact and smaller processed form. In vitro, DNA-PK phosphorylates several transcription factors and other DNA-binding proteins and is believed to play a role in DNA damage recognition, repair and transcription. There is evidence to s µggest that DNA-PKcs may be a critical target for proteolysis by a caspase in apoptosis.
Other Names:
PRKDC, XRCC7 , p460, DNPK1, HYRC, HYRC1 , DNAPK , p350
Primary Accession: P78527
Gene Name: PRKDC
Gene ID: 5591
Concentration (mg/ml): 0.5 mg/ml
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