DNA PK (PRKDC) polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP7053b
Catalog Number: AC-AP7053b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3465/3466
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3465/3466
Applications: IHC-P, WB
Datasheet
Request Information
Background:
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM]
Other Names:
DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNA-PKcs, DNPK1, p460, PRKDC, HYRC, HYRC1
Target/Specificity:
This DNA PK (PRKDC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4075~4104 amino acids from the C-terminal region of human PRKDC.
Antigen Region:
4075-4104
Antigen Type: Synthetic Peptide
Gene Name: PRKDC
Gene ID: 5591
Primary Accession: P78527
NCBI Accession: NP_001075109.1;NP_008835.5
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM]
Other Names:
DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNA-PKcs, DNPK1, p460, PRKDC, HYRC, HYRC1
Target/Specificity:
This DNA PK (PRKDC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4075~4104 amino acids from the C-terminal region of human PRKDC.
Antigen Region:
4075-4104
Antigen Type: Synthetic Peptide
Gene Name: PRKDC
Gene ID: 5591
Primary Accession: P78527
NCBI Accession: NP_001075109.1;NP_008835.5
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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