Dlx-5 polyclonal, anti-human, mouse, rat

Dlx-5 polyclonal, anti-human, mouse, rat

€470.00
In stock
SKU
AC-AP69543
Catalog Number: AC-AP51449
Size: 100 µl
Host: Rabbit
Applications: WB, ICC, IHC-P, E
Datasheet
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Background:
Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

Other Names:
DLX5; Homeobox protein DLX-5

Antigen Type: synthetic peptide

Antigen Type: DLX5
Gene ID: 1749
Primary Accession: P56178
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