DNA pol δ 3 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5699
Background:
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol α, β, δ and ε. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol δ 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol δ.
Alternative Name:
DNA polymerase delta subunit 3, DNA polymerase delta subunit p66, POLD3, KIAA0039, DNA pol δ3, DNA polδ3, DNApolδ3, DNA pol δ p66, DNA polδ p66
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: DNA pol δ 3 polyclonal antibody detects endogenous levels of DNA pol δ 3 protein.
Immunogen:
Synthetic peptide, corresponding to the 421-466 of Human DNA pol δ 3.
MW: ~ 51 kDa
Swis Prot.: Q15054
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol α, β, δ and ε. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol δ 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol δ.
Alternative Name:
DNA polymerase delta subunit 3, DNA polymerase delta subunit p66, POLD3, KIAA0039, DNA pol δ3, DNA polδ3, DNApolδ3, DNA pol δ p66, DNA polδ p66
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: DNA pol δ 3 polyclonal antibody detects endogenous levels of DNA pol δ 3 protein.
Immunogen:
Synthetic peptide, corresponding to the 421-466 of Human DNA pol δ 3.
MW: ~ 51 kDa
Swis Prot.: Q15054
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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