DNA pol δ cat (D1091) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3850
Background:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and togther with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).
Alternative Name:
DNA polymerase delta catalytic subunit, DNA polymerase subunit delta p125, POLD1, POLD, DNA pol δ p125, DNA polδ p125
Application Dilution: IHC: 1:50~1:200
Specificity: NA pol δ cat (D1091) polyclonal antibody detects endogenous levels of CNA pol δ cat protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 1060-1110 of Human DNA pol δ cat.
MW: ~ 125 kDa
Swis Prot.: P28340
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and togther with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).
Alternative Name:
DNA polymerase delta catalytic subunit, DNA polymerase subunit delta p125, POLD1, POLD, DNA pol δ p125, DNA polδ p125
Application Dilution: IHC: 1:50~1:200
Specificity: NA pol δ cat (D1091) polyclonal antibody detects endogenous levels of CNA pol δ cat protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 1060-1110 of Human DNA pol δ cat.
MW: ~ 125 kDa
Swis Prot.: P28340
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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