DNA Polymerase β polyclonal, anti-human, mouse, rat, zebrafish

Background:
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

Alternative Name:
POLB, DNA directed DNA polymerase beta, DNA pol beta, DNA polymerase beta, DNA polymerase beta subunit, DPOLB, MGC125976, Pol B, Pol beta, POLB, Polymerase (DNA directed) beta,

Application Dilution:
WB:1:500
IHC:1:50-1:200
ICC:1:20-1:50
IP:1:10-1:20

Specificity: DNA Polymerase β polyclonal antibody detects endogenous levels of DNA Polymerase β protein.

Immunogen:
Recombinant protein

MW: 38 kDa

Swiss-Prot: P06746(Human) Q8K409(Mouse) P06766(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.