DNA2 Polyclonal Antibody

Background:
This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
DNA replication ATP-dependent helicase-like homolog, DNA replication helicase 2 homolog, DNA replication helicase 2, yeast, homolog of, DNA replication helicase 2-like, DNA replication helicase/nuclease 2, DNA2, DNA2-like helicase, DNA2L, DNA2L, HDNA2, KIAA0083, PEOA6, SCKL8

Immunogen: Fusion protein of human DNA2

Swissprot: P51530
Gene Accession: BC111740

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.84 mg/mL
Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.