CD207 polyclonal, anti-human

CD207 polyclonal, anti-human

€470.00
In stock
SKU
AC-AP73458
Catalog Number: AC-AP60743
Size: 100 µl
Host: Rabbit
Applications: WB, IHC
Datasheet
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Background:
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Other Names:
CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207

Antigen Type: synthetic peptide

Antigen Type: CD207
Gene ID: 50489
Primary Accession: Q9UJ71
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