DNAJC2 Polyclonal Antibody

Background:
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

Synonyms:
AU020218, DnaJ (Hsp40) homolog subfamily C member 2, DnaJ homolog subfamily C member 2, Dnajc2, DNJC2, M phase phosphoprotein 11, M-phase phosphoprotein 11, MGC105894, MIDA1, MPHOSPH11, MPP11, OTTMUSP00000031226, ZRF1, Zrf2, ZUO1, Zuotin related factor 1, Zuotin related factor 2, Zuotin-related factor 1

Immunogen: Synthetic peptide of human DNAJC2

Swissprot: Q99543
Gene Accession: NP055192

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.2 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.