DNAL1 Polyclonal Antibody

Background:
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (PubMed:21496787).

Research Area: Signaling transduction

Synonyms:
axonemal, Axonemal dynein light chain 1, Axonemal dynein light chain, C14orf168, Chromosome 14 open reading frame 168, CILD16, DNAL 1, dnal1, DNAL1, Dynein axonemal light chain 1, Dynein light chain 1, Dynein light chain 1 axonemal, MGC12435

Immunogen: Recombinant Dynein light chain 1, axonemal protein

Swissprot: Q4LDG9

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 2 mg/mL
Dilution: IHC 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-164197