DNM1 Polyclonal Antibody

Background:
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
B dynamin, D100, DNM 1, DNM, DNM1, DYN1, Dynamin, Dynamin-1, Dynamin1

Immunogen: Synthetic peptide of human DNM1

Swissprot: Q05193
Gene Accession: NP_004399

Calculated MW: 97 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6402/sc-6401/sc-58260/sc-11362