Dnmt3A/Dnmt3A2 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP1023b
Catalog Number: AC-AP1023b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12504
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12504
Applications: WB
Datasheet
Request Information
Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. DNMT3A is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Other Names:
DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, MHsaIIIA, DNMT3A
Target/Specificity:
This Dnmt3A/Dnmt3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the C-terminal region of human Dnmt3A/Dnmt3A2.
Antigen Region:
723-752
Antigen Type: Synthetic Peptide
Gene Name: DNMT3A
Gene ID: 1788
Primary Accession: Q9Y6K1
NCBI Accession: NP_072046.2;NP_715640.2;NP_783328.1;NP_783329.1
Other Accession: Q1LZ53; O88508
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. DNMT3A is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Other Names:
DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, MHsaIIIA, DNMT3A
Target/Specificity:
This Dnmt3A/Dnmt3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the C-terminal region of human Dnmt3A/Dnmt3A2.
Antigen Region:
723-752
Antigen Type: Synthetic Peptide
Gene Name: DNMT3A
Gene ID: 1788
Primary Accession: Q9Y6K1
NCBI Accession: NP_072046.2;NP_715640.2;NP_783328.1;NP_783329.1
Other Accession: Q1LZ53; O88508
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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