Dnmt3a polyclonal, anti-human, mouse, rat
€0.00
In stock
SKU
AC-AP1034a
Catalog Number: AC-AP1034a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01852
Applications: IHC-P, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01852
Applications: IHC-P, WB
Datasheet
Request Information
Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Other Names:
DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, MHsaIIIA, DNMT3A
Target/Specificity:
This Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from human Dnmt3a.
Antigen Region:
457-486
Antigen Type: Synthetic Peptide
Gene Name: DNMT3A
Gene ID: 1788
Primary Accession: Q9Y6K1
NCBI Accession: NP_072046.2;NP_715640.2;NP_783328.1;NP_783329.1
Other Accession: Q1LZ53; O88508; Q4W5Z4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Other Names:
DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, MHsaIIIA, DNMT3A
Target/Specificity:
This Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from human Dnmt3a.
Antigen Region:
457-486
Antigen Type: Synthetic Peptide
Gene Name: DNMT3A
Gene ID: 1788
Primary Accession: Q9Y6K1
NCBI Accession: NP_072046.2;NP_715640.2;NP_783328.1;NP_783329.1
Other Accession: Q1LZ53; O88508; Q4W5Z4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review