DNMT3A Polyclonal Antibody

Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
DNMT3A, DNMT3A2, M.HsaIIIA, TBRS, DNMT3A

Immunogen: Recombinant protein of human DNMT3A

Swissprot: Q9Y6K1
Gene ID: 1788

Calculated MW: 16 kDa/81 kDa/101 kDa
Observed MW: 95 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.