DNTT antibody (clone 4H5), anti-human
€435.00
In stock
SKU
AC-AT1808a
Catalog Number: AC-AT1808a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT1808a">Request Information
Background:
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Other Names:
DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase, DNTT, TDT
Antigen Type:
Recombinant Protein
Gene Name: DNTT
Gene ID: 1791
NCBI Accession: NP_001017520.1;NP_004079.3
Primary Accession: P04053
Other Accession: BC012920
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Other Names:
DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase, DNTT, TDT
Antigen Type:
Recombinant Protein
Gene Name: DNTT
Gene ID: 1791
NCBI Accession: NP_001017520.1;NP_004079.3
Primary Accession: P04053
Other Accession: BC012920
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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