DNTT polyclonal, anti-mouse, rat
€388.00
In stock
SKU
BS7996
Background:
Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3'-hydroxyl end of DNA primers without template direction. The enzyme thus provides a unique method for the labeling of the 3' termini of DNA. The human TdT gene maps to chromosome 10q23-q24 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. TdT is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.
Alternative Name:
Deoxynucleotidyltransferase terminal, DNA nucleotidylexotransferase, DNTT, Nucleosidetriphosphate DNA deoxynucleotidylexotransferase, TDT, TDT_HUMAN, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal deoxyribonucleotidyltransferase, Terminal transferase,
Application Dilution: WB: 1:500 - 1:2000
Specificity: DNTT polyclonal antibody detects endogenous levels of DNTT protein.
Immunogen:
Recombinant full length Human DNTT.
MW: ~ 70 kDa
Swis Prot.: P04053
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3'-hydroxyl end of DNA primers without template direction. The enzyme thus provides a unique method for the labeling of the 3' termini of DNA. The human TdT gene maps to chromosome 10q23-q24 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. TdT is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.
Alternative Name:
Deoxynucleotidyltransferase terminal, DNA nucleotidylexotransferase, DNTT, Nucleosidetriphosphate DNA deoxynucleotidylexotransferase, TDT, TDT_HUMAN, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal deoxyribonucleotidyltransferase, Terminal transferase,
Application Dilution: WB: 1:500 - 1:2000
Specificity: DNTT polyclonal antibody detects endogenous levels of DNTT protein.
Immunogen:
Recombinant full length Human DNTT.
MW: ~ 70 kDa
Swis Prot.: P04053
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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