DOC11 polyclonal antibody, anti-human, mouse

Background:
The DHR-2 domain is necessary for the GEF activity.,Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR-1 (CZH-1) domain.,Contains 1 DHR-2 (CZH-2) domain.,Contains 1 PH domain.,subunit:Interacts with CDC42.,

Research Area: Cell biology, Epigenetics and nuclear signaling

Synonyms: Dedicator of cytokinesis protein 11 , Activated Cdc42-associated guanine nucleotide exchange factor, ACG, Zizimin-2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year