DOCK 180 Polyclonal Antibody

Background:
dedicator of cytokinesis 1(DOCK1) Homo sapiens This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],

Alternative Names:
DOCK1, Dedicator of cytokinesis protein 1, 180 kDa protein downstream of CRK, DOCK180

Immunogen: The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 215

GeneID: DOCK1

Storage: -20°C/1 year

NOTE: For Research Use Only