DOCK 2 Polyclonal Antibody

Background:
dedicator of cytokinesis 2(DOCK2) Homo sapiens The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016],

Alternative Names:
DOCK2, KIAA0209, Dedicator of cytokinesis protein 2

Immunogen: Synthesized peptide derived from the Internal region of human DOCK 2.

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

GeneID: DOCK2

Storage: -20°C/1 year

NOTE: For Research Use Only