DOK2 Polyclonal Antibody

Background:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Research Area: Cancer, Signal Transduction

Synonyms:
DOK2, p56DOK, p56dok-2

Immunogen: Recombinant fusion protein of human DOK2 (NP_003965.2).

Swissprot: O60496
Gene ID: 9046

Calculated MW: 45 kDa
Observed MW: 45 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.