DOK7 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13568a
Background:
The protein encoded by this gene is essential forneuromuscular synaptogenesis. The protein functions in aneuralactivation of muscle-specific receptor kinase, which is requiredfor postsynaptic differentiation, and in the subsequent clusteringof the acetylcholine receptor in myotubes. This protein can alsoinduce autophosphorylation of muscle-specific receptor kinase.Mutations in this gene are a cause of familial limb-girdlemyasthenia autosomal recessive, which is also known as congenitalmyasthenic syndrome type 1B. Alternative splicing results inmultiple transcript variants.
Other Names:
Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13568a was selected from the N-term region of DOK7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DOK7
Gene ID: 285489
Primary Accession: Q18PE1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is essential forneuromuscular synaptogenesis. The protein functions in aneuralactivation of muscle-specific receptor kinase, which is requiredfor postsynaptic differentiation, and in the subsequent clusteringof the acetylcholine receptor in myotubes. This protein can alsoinduce autophosphorylation of muscle-specific receptor kinase.Mutations in this gene are a cause of familial limb-girdlemyasthenia autosomal recessive, which is also known as congenitalmyasthenic syndrome type 1B. Alternative splicing results inmultiple transcript variants.
Other Names:
Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13568a was selected from the N-term region of DOK7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DOK7
Gene ID: 285489
Primary Accession: Q18PE1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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