DOK7 polyclonal (N-term), anti-mouse
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In stock
SKU
AC-AP13568a
Catalog Number: AC-AP13568a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32528
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32528
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
Other Names:
Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25
Target/Specificity:
This DOK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human DOK7.
Antigen Region:
26-55
Antigen Type: Synthetic Peptide
Gene Name: DOK7
Gene ID: 285489
Primary Accession: Q18PE1
NCBI Accession: NP_001158145.1;NP_001243825.1;NP_775931.3
Other Accession: NP_001158145.1;NP_775931.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
Other Names:
Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25
Target/Specificity:
This DOK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human DOK7.
Antigen Region:
26-55
Antigen Type: Synthetic Peptide
Gene Name: DOK7
Gene ID: 285489
Primary Accession: Q18PE1
NCBI Accession: NP_001158145.1;NP_001243825.1;NP_775931.3
Other Accession: NP_001158145.1;NP_775931.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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