Dopamine D2 Receptor polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Dopamine receptor D2, also known as D2R or D2DR is a protein that in humans is encoded by the DRD2 gene. DRD2 gene is mapped to 11q23.2. This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

Description:
Rabbit IgG polyclonal antibody for D (2) dopamine receptor (DRD2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
D(2) dopamine receptor antibody, D2 dopamine receptor antibody, D2DR antibody, D2R antibody, Dopamine D2 receptor antibody, Dopamine receptor D2 antibody, DRD 2 antibody, DRD2 antibody, DRD2_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine D2 Receptor(360-375aa RRKLSQQKEKKATQML), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine D2 Receptor(360-375aa RRKLSQQKEKKATQML), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.