Dopamine Receptor D3 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
DRD3 is a dopamine receptor that differs in its pharmacology and signaling system from the D1 and D2 receptors and represents both an autoreceptor and a postsynaptic receptor. DRD3 is localized to limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. The DRD3 gene, which is mapped to chromosome 3, is like the DRD2 gene but unlike most other members of this superfamily and it contains introns, 5 in number. The position of 2 of the introns corresponds to that of introns in DRD2. The D3 receptor appeared to mediate some of the effects of antipsychotic drugs and drugs used in the treatment of Parkinson disease, which were previously though to interact only with D2 receptors.

Description:
Rabbit IgG polyclonal antibody for D (3) dopamine receptor (DRD3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
3dopamine receptor antibody, D antibody, D(3) dopamine receptor antibody, Dopamine D3 receptor antibody, Dopamine receptor D3 antibody, DRD3 antibody, DRD3_HUMAN antibody, ETM1 antibody, FET1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine Receptor D3(352-367aa NTHCQTCHVSPELYSA), different from the related rat and mouse sequences by two amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine Receptor D3(352-367aa NTHCQTCHVSPELYSA), different from the related rat and mouse sequences by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.