Dopamine Receptor D5 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
D(1B) dopamine receptor(DRD5), also called DRD1B or DRD1L2 is a protein that in humans is encoded by the DRD5 gene. This gene is mapped to 4p16.1. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. Compared with DRD1, DRD5 displayed a higher affinity for dopamine and was able to stimulate a biphasic rather than a monophasic intracellular accumulation of cAMP.

Description:
Rabbit IgG polyclonal antibody for D (1B) dopamine receptor (DRD5) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
D(1B) dopamine receptor antibody, D(5) dopamine receptor antibody, D1 beta dopamine receptor antibody, D1B dopamine receptor antibody, D1beta dopamine receptor antibody, D5 dopamine receptor antibody, DBDR antibody, Dopamine D5 receptor antibody, Dopamine receptor D1B antibody, DRD 1B antibody, DRD 5 antibody, DRD1B antibody, DRD1L2 antibody, DRD5 antibody, DRD5_HUMAN antibody, MGC10601 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Dopamine Receptor D5(388-407aa LISYNQDTVFHREIAAAYVH), different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.