DPH1 antibody (clone 2C5), anti-human
€435.00
In stock
SKU
AC-AT1812a
Catalog Number: AC-AT1812a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF
Request Information AC-AT1812a">Request Information
Background:
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).
Other Names:
Diphthamide biosynthesis protein 1, DPH1 homolog, HsDph1, Diphthamide biosynthesis protein 2 homolog-like 1, DPH-like 1, DPH2-like 1, Diphthamide biosynthesis protein 2-like, Ovarian cancer-associated gene 1 protein, DPH1, DPH2L, DPH2L1, OVCA1
Antigen Type:
Recombinant Protein
Gene Name: DPH1 {ECO:0000303|PubMed:26220823}
Gene ID: 1801
NCBI Accession: NP_001374.3
Primary Accession: Q9BZG8
Other Accession: NM_001383
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).
Other Names:
Diphthamide biosynthesis protein 1, DPH1 homolog, HsDph1, Diphthamide biosynthesis protein 2 homolog-like 1, DPH-like 1, DPH2-like 1, Diphthamide biosynthesis protein 2-like, Ovarian cancer-associated gene 1 protein, DPH1, DPH2L, DPH2L1, OVCA1
Antigen Type:
Recombinant Protein
Gene Name: DPH1 {ECO:0000303|PubMed:26220823}
Gene ID: 1801
NCBI Accession: NP_001374.3
Primary Accession: Q9BZG8
Other Accession: NM_001383
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
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