DPP8 Antibody (C-term) Blocking Peptide

Background:
DPP8 is a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function.

Other Names:
Dipeptidyl peptidase 8, DP8, Dipeptidyl peptidase IV-related protein 1, DPRP-1, Dipeptidyl peptidase VIII, DPP VIII, Prolyl dipeptidase DPP8, DPP8, DPRP1

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6506b was selected from the C-term region of human DPP8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: DPP8 {ECO:0000303|PubMed:11012666, ECO:0000312|HGNC:HGNC:16490}

Gene ID: 54878
Primary Accession: Q6V1X1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.