DPYD antibody (clone 7D4), anti-human
€435.00
In stock
SKU
AC-AT1815a
Catalog Number: AC-AT1815a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT1815a">Request Information
Background:
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPYD
Antigen Type:
Recombinant Protein
Gene Name: DPYD (HGNC:3012)
Gene ID: 1806
NCBI Accession: NP_000101.2;NP_001153773.1
Primary Accession: Q12882
Other Accession: NM_000110
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPYD
Antigen Type:
Recombinant Protein
Gene Name: DPYD (HGNC:3012)
Gene ID: 1806
NCBI Accession: NP_000101.2;NP_001153773.1
Primary Accession: Q12882
Other Accession: NM_000110
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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