DPYD polyclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO11070
Catalog Number: AC-ABO11070
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for Dihydropyrimidine dehydrogenase[NADP(+)](DPYD) detection. Tested with WB in Human;Mouse;Rat.Protein Name: Dihydropyrimidine dehydrogenase [NADP(+)](DHPDHase/DPD)
Protein Function:
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
Other Names: Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, 1.3.1.2, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPYD
Subcellular Localization: Cytoplasm.
Tissue Specificity: Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
Gene ID: 1806
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DPYD(33-52aa AKKLDKKHWKRNPDKNCFNC), different from the related rat and mouse sequences by one amino acid.
Calculated MW: 111401
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
Other Names: Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, 1.3.1.2, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPYD
Subcellular Localization: Cytoplasm.
Tissue Specificity: Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
Gene ID: 1806
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DPYD(33-52aa AKKLDKKHWKRNPDKNCFNC), different from the related rat and mouse sequences by one amino acid.
Calculated MW: 111401
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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