DPYSL3 polyclonal, anti-human, mouse, rat

Background:
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. Developing neurons in the adult hippocampus of mammals, known as the dentate gyrus, express CRMP-4. Rodent neocortical neurons express CRMP-4 in the perikaryon, in neurites and at growth cones.

Synonyms: DRP3, ULIP, CRMP4, DRP-3, LCRMP, CRMP-4, ULIP-1

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human DPYSL3

Gene Symbol: DPYSL3

Gene ID: 1809

Swiss prot: Q14195

Calculated MW: 62 kDa

Recommended dilution:
WB 1:200-1000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.