DPYSL3 Polyclonal Antibody

Background:
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. Developing neurons in the adult hippocampus of mammals, known as the dentate gyrus, express CRMP-4. Rodent neocortical neurons express CRMP-4 in the perikaryon, in neurites and at growth cones.

Research Area: Cancer, Neuroscience

Synonyms:
Collapsin response mediator protein 4, Collapsin response mediator protein 4 long, CRMP 4, CRMP-4, CRMP4, Dihydropyrimidinase like 3, Dihydropyrimidinase related protein 3, Dihydropyrimidinase-related protein 3, DPYL3, DPYSL3, DRP 3, DRP-3, DRP3, LCRMP, TUC4, ULIP 1, ULIP, ULIP-1, ULIP1, UNc 33 like phosphoprotein 1, Unc 33 like phosphoprotein, Unc-33-like phosphoprotein 1

Immunogen: Recombinant protein of human DPYSL3

Swissprot: Q14195
Gene Accession: NP_001378

Calculated MW: 62 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-27321/sc-27323