DR1 polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP17826c
Catalog Number: AC-AP17826c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37581
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37581
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription
Other Names:
Protein Dr1, Down-regulator of transcription 1, Negative cofactor 2-beta, NC2-beta, TATA-binding protein-associated phosphoprotein, DR1
Target/Specificity:
This DR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-112 amino acids from the Central region of human DR1.
Antigen Region:
83-112
Antigen Type: Synthetic Peptide
Gene Name: DR1
Gene ID: 1810
Primary Accession: Q01658
NCBI Accession: NP_001929.1
Other Accession: Q5XI68; Q91WV0; Q5ZMV3; NP_001929.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription
Other Names:
Protein Dr1, Down-regulator of transcription 1, Negative cofactor 2-beta, NC2-beta, TATA-binding protein-associated phosphoprotein, DR1
Target/Specificity:
This DR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-112 amino acids from the Central region of human DR1.
Antigen Region:
83-112
Antigen Type: Synthetic Peptide
Gene Name: DR1
Gene ID: 1810
Primary Accession: Q01658
NCBI Accession: NP_001929.1
Other Accession: Q5XI68; Q91WV0; Q5ZMV3; NP_001929.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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