DR3 polyclonal, anti-human

Quantity: 100 µg

Background:
TNFRSF25(Tumor Necrosis Factor Receptor Superfamily Member 25), also known as LARD, APO3, DR3 or TNFR25, is a protein that in humans is encoded by the TNFRSF25 gene. Members of the mammalian tumor necrosis factor receptor(TNFR) family are cell-surface proteins that interact with a corresponding TNF-related ligand family. By fluorescence in situ hybridization, Marsters et al.(1996) mapped the Apo3 gene to 1p36.3. Marsters et al.(1996) showed that ectopic expression of Apo3 in mammalian cells triggered apoptosis and activated the transcription factor NF-kappa-B. They suggested that, like TNFR1, Apo3 may regulate distinct signaling pathways in different cellular contexts.

Description:
Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) detection. Tested with WB in Human.

Synonyms:
Apo 3 antibody, Apo-3 antibody, Apo3 antibody, Apoptosis inducing receptor AIR antibody, Apoptosis inducing receptor antibody, Apoptosis mediating receptor antibody, Apoptosis mediating receptor DR 3 antibody, Apoptosis mediating receptor DR3 antibody, Apoptosis mediating receptor TRAMP antibody, Apoptosis-inducing receptor AIR antibody, Apoptosis-mediating receptor DR3 antibody, Apoptosis-mediating receptor TRAMP antibody, DDR 3 antibody, DDR3 antibody, Death domain receptor 3 antibody, Death Receptor 3 antibody, Death receptor beta antibody, DR 3 antibody, LARD antibody, Lymphocyte associated receptor of death antibody, Lymphocyte-associated receptor of death antibody, Protein WSL antibody, Protein WSL-1 antibody, TNFRSF 12 antibody, TNFRSF 25 antibody, TNFRSF12 antibody, TNFRSF25 antibody, TNR25_HUMAN antibody, TR 3 antibody, TR3 antibody, TRAMP antibody, Translocating chain association membrane protein antibody, Tumor necrosis factor receptor superfamily member 12 antibody, Tumor necrosis factor receptor superfamily member 25 antibody, WSL 1 antibody, WSL antibody, WSL LR antibody, WSL protein antibody, WSL1 antibody, WSL1 protein antibody, WSLLR antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human DR3(73-94aa CPQDTFLAWENHHNSECARCQA).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.